Identification and validation of core genes for type 2 diabetes mellitus by integrated analysis of single-cell and bulk RNA-sequencing
Abstract Background The exact mechanisms of type 2 diabetes mellitus (T2DM) remain largely unknown.We intended to authenticate critical genes linked to T2DM progression by tandem single-cell sequencing and general transcriptome sequencing data.Methods T2DM single-cell RNA-sequencing data were submitted by the Gene Expression Omnibus (GEO) database